AP BIOLOGY

BIOCHEMISTRY

ENZYMES AND METABOLISM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The lock-and-key analogy for enzymes applies to the specificity of enzymes ____
A
as they form their tertiary and quaternary structure
B
binding to their substrate
C
interacting with water
D
interacting with ions
Explanation: 

Detailed explanation-1: -Lock-and-key model is a model for enzyme-substrate interaction suggesting that the enzyme and the substrate possess specific complementary geometric shapes that fit exactly into one another. Enzymes are highly specific. They must bind to a specific substrate before they can catalyze a chemical reaction.

Detailed explanation-2: -A Lock and Key analogy may be used to describe the fundamental action of a single substrate enzyme. In this case, the enzyme is the lock, and the substrate is the key. Only the correct size key, which is the substrate, enters the keyhole, which is the active site of the lock, which is the enzyme.

Detailed explanation-3: -The specific action of an enzyme with a single substrate can be explained using a Lock and Key analogy first postulated in 1894 by Emil Fischer. In this analogy, the lock is the enzyme and the key is the substrate. Only the correctly sized key (substrate) fits into the keyhole (active site) of the lock (enzyme).

There is 1 question to complete.