AP BIOLOGY

Detailed explanation-1: -Substrates bind to the active site of the enzyme through hydrogen bonds, hydrophobic interactions, ionic bonding, temporary covalent interactions (Van der Waals’) or a combination of all of these to form the enzyme-substrate complex.

Detailed explanation-2: -The part of the enzyme where the substrate binds is called the active site (since that’s where the catalytic “action” happens). A substrate enters the active site of the enzyme. This forms the enzyme-substrate complex.

Detailed explanation-3: -The enzyme active site is the binding site for catalytic and inhibition reactions of enzyme and substrate; structure of active site and its chemical characteristic are of specific for the binding of a particular substrate.