AP BIOLOGY

Detailed explanation-1: -When an enzyme denatures, its active site changes its shape, as you can see in this diagram. This is because the protein structure of the enzyme has changed. You might notice that the active site is no longer a complementary shape to a specific substrate molecule.

Detailed explanation-2: -Denaturation of enzymes causes bonds to be broken, structure to be disrupted and it stops functioning. This happens to enzymes when they are exposed to extreme, unsuitable conditions, for instance, high temperatures or extreme pH levels.

Detailed explanation-3: -Enzyme denaturation happens when the structure of a protein and its functional group undergo conformational changes, resulting in inactivity. Denatured proteins have a looser, more random structure, and the majority of them are insoluble.