AP BIOLOGY

Detailed explanation-1: -Therefore, oriented mitotic division of epithelial cells, especially ESCs, is particularly important for wound healing.

Detailed explanation-2: -Epithelialization. All dermal wounds heal by three basic mechanisms: contraction, connective tissue matrix deposition and epithelialization. Wounds that remain open heal by contraction; the interaction between cells and matrix results in movement of tissue toward the center of the wound.

Detailed explanation-3: -Cytokines. Cytokines have emerged as important mediators of wound healing events. By definition, a cytokine is a protein mediator, released from various cell sources, which binds to cell surface receptors to stimulate a cell response.

Detailed explanation-4: -Replacement and regeneration of new cells-Regeneration and replacement of worn-out and damaged tissues is a very important function of mitosis in living organisms. Mitosis helps in the production of identical copies of cells and thus helps in repairing the damaged tissue or replacing the worn-out cells.