AP BIOLOGY

CELL DIVISION

CELL DIVISION AND CANCEROUS CELLS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Cancer is a disease caused by mutations. Yet in most instances, if a parent tragically dies from cancer, this does not put their child at greater risk than a person whose parents do not develop cancer. How can cancer be caused by mutations and yet not be heritable?
A
Most cancers arise from mutations in germ line cells.
B
Mutations cause cancer occur in sex cells only.
C
Mutations caused by environmental agents, such as tobacco smoke, occur in somatic cells.
D
Mutations that cause cancer are specific and cannot be passed on regardless of the type of cell they occur in.
Explanation: 

Detailed explanation-1: -To understand what this means, consider the following: When a mutation gives a cancer cell a growth advantage, it can make more copies of itself than a normal cell can-and its offspring can outperform their noncancerous counterparts in the competition for resources.

Detailed explanation-2: -A damaged p53 gene can result in the cell behaving as if there are no mutations (Figure 6.8). This allows cells to divide, propagating the mutation in daughter cells and allowing the accumulation of new mutations. In addition, the damaged version of p53 found in cancer cells cannot trigger cell death.

Detailed explanation-3: -Leading risk factors for preventable cancers are smoking, getting too much ultraviolet (UV) radiation from the sun or tanning beds, being overweight or having obesity, and drinking too much alcohol.

Detailed explanation-4: -Cancer is a large group of diseases that can start in almost any organ or tissue of the body when abnormal cells grow uncontrollably, go beyond their usual boundaries to invade adjoining parts of the body and/or spread to other organs.

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