AP BIOLOGY

Detailed explanation-1: -Superficially, the connection between the cell cycle and cancer is obvious: cell cycle machinery controls cell proliferation, and cancer is a disease of inappropriate cell proliferation. Fundamentally, all cancers permit the existence of too many cells.

Detailed explanation-2: -Cancer is a disease caused when cells divide uncontrollably and spread into surrounding tissues. Cancer is caused by changes to DNA. Most cancer-causing DNA changes occur in sections of DNA called genes. These changes are also called genetic changes.

Detailed explanation-3: -In summary, cancer cells have defects in normal cellular functions that allow them to divide, invade the surrounding tissue, and spread by way of vascular and/or lymphatic systems. These defects are the result of gene mutations sometimes caused by infectious viruses.

Detailed explanation-4: -Once these crucial Cell Cycle genes start behaving abnormally, cancer cells start to proliferate wildly by repeated, uncontrolled mitosis.

Detailed explanation-5: -Cancer is basically a disease of uncontrolled cell division. Its development and progression are usually linked to a series of changes in the activity of cell cycle regulators.