AP BIOLOGY

Detailed explanation-1: -During anaphase identical sister chromatids separate and move towards opposite poles of the mitotic spindle . In the spindle, kinetochore microtubules have their plus ends embedded in the kinetochore and their minus ends at the spindle pole.

Detailed explanation-2: -Anaphase: During anaphase, the centromere splits, allowing the sister chromatids to separate. The kinetochore spindle fibers shorten, allowing for 46 of the newly-freed chromatids to be dragged to one end of the cell and the remaining 46 chromatids to be dragged to the opposite end of the cell.

Detailed explanation-3: -During mitosis, several types of microtubules are active. The motor proteins associated with the interpolar microtubules drive the assembly of the spindle. Note the other types of microtubules involved in anchoring the spindle pole and pulling apart the sister chromatids.

Detailed explanation-4: -The phases of mitosis can be described as follows: During prophase chromatin condenses to form discrete chromosomes. During metaphase microtubules attach to the kinetochores and chromatids begin segregating. During anaphase sister chromatids have been separated and reside at opposite poles of the cell.

Detailed explanation-5: -The sister chromatids are pairs of identical copies of DNA joined at a point called the centromere. During anaphase, each pair of chromosomes is separated into two identical, independent chromosomes. The chromosomes are separated by a structure called the mitotic spindle.