AP BIOLOGY

CELL DIVISION

CELL DIVISION AND CANCEROUS CELLS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Give the correct sequence of apoptosis:1. Nucleus begins to break2. Nucleus condensation and formation of bleb3. Phagocytosis of apoptotic bodies.
A
1, 2, 3
B
2, 3, 1
C
3, 2, 1
D
2, 1, 3
Explanation: 

Detailed explanation-1: -To illustrate these apoptosis events and how to detect them, Bio-Rad has created a pathway which divides apoptosis into four stages: induction, early phase, mid phase and late phase (Figure 1).

Detailed explanation-2: -There are 4 stages of apoptosis: the initiation or stimulus for cell death, the active programmed cell death when the events become irreversible, phagocytosis of the dead cellular material, and inhibitory mechanisms of apoptosis.

Detailed explanation-3: -The key step in apoptosis is the release of the protein cytochrome c and other apoptotic factors from the mitochondria into the cell interior. After this step, apoptosis induction is irreversible and cell’s fate is sealed. In order to allow this process, the mitochondrial membrane must be permeable.

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