AP BIOLOGY

Detailed explanation-1: -In prophase of mitosis, specialized regions on centromeres called kinetochores attach chromosomes to spindle fibers.

Detailed explanation-2: -Spindle fibres attach themselves to the kinetochore of the chromosomes and help to pull sister chromatids towards opposite poles. Kinetochores are proteinaceous disc-like structures present on the sides of the centromere.

Detailed explanation-3: -Chromatid During cell division, spindle fibers attach to the centromere and pull each of the sister chromatids to opposite sides of the cell.

Detailed explanation-4: -Chromosomes attach to spindle fibers during metaphase. Chromosomes contain a cell’s DNA or genetic information. Before entering mitosis, the cell duplicates its DNA during the synthesis stage of the cell cycle. This DNA must be split in order to place one of each copy into two separate cells.

Detailed explanation-5: -Centromere The centromere appears as a constricted region of a chromosome and plays a key role in helping the cell divide up its DNA during division (mitosis and meiosis). Specifically, it is the region where the cell’s spindle fibers attach.