CELL DIVISION
CELL DIVISION AND CANCEROUS CELLS
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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protein synthesis, organelle number increase, cell size increases, Cyclin D is expressed
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DNA is replicated, triggered by Cyclin A
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protein synthesis, organelle number increase, cell size increases, Cyclin B is expressed to promote spindle formation
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Separation of sister chromatids into genetically identical nuclei
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Detailed explanation-1: -The S phase of a cell cycle occurs during interphase, before mitosis or meiosis, and is responsible for the synthesis or replication of DNA. In this way, the genetic material of a cell is doubled before it enters mitosis or meiosis, allowing there to be enough DNA to be split into daughter cells.
Detailed explanation-2: -S phase is the period during which DNA replication occurs.
Detailed explanation-3: -Once activated, the S phase cyclins Clb5 and Clb6 in complex with Cdk phosphorylate Sld2 and Sld3 to initiate the formation of the Sld2–Sld3–Dpb11 complex. This complex mediates the activation of DNA replication66–68. Cyclin specificity has an important role in ordering cell cycle events18.
Detailed explanation-4: -In S phase, cyclin A and its partner, CDK2, phosphorylate substrates that commence DNA replication from preformed replication initiation complexes. Cyclin A-CDK2 is also required to coordinate the end of S phase with activation of the mitotic cyclin-CDKs.