AP BIOLOGY

Detailed explanation-1: -Martha’s colon cancer has not spread. When abnormal cells are only found in the tissue of origin, this refers to: in situ.

Detailed explanation-2: -The spread of cancer cells from the place where they first formed to another part of the body. In metastasis, cancer cells break away from the original (primary) tumor, travel through the blood or lymph system, and form a new tumor in other organs or tissues of the body.

Detailed explanation-3: -Metastasis is a word used to describe the spread of cancer. Unlike normal cells, cancer cells have the ability to grow outside of the place in your body where they originated. When this happens, it’s called metastatic cancer, advanced cancer or Stage IV cancer.

Detailed explanation-4: -Also called stage 0 disease. Carcinoma in situ (CIS) is a group of abnormal cells that are found only in the place where they first formed in the body (see left panel). These abnormal cells may become cancer and spread to nearby normal tissue (see right panel).

Detailed explanation-5: -Carcinoma in situ refers to cancer in which abnormal cells have not spread beyond where they first formed. The words “in situ” mean “in its original place.” These in situ cells are not malignant, or cancerous. However, they can sometime become cancerous and spread to other nearby locations.