CELL DIVISION
CELL DIVISION AND CANCEROUS CELLS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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are mutated forms of tumor suppressor genes
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are mutated forms of genes that code for proteins that normally assist in apoptosis
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are mutated genes that inhibit the cell cycle
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are mutated genes that code for proteins which activate cell division too often or at the improper time
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Detailed explanation-1: -The correct answer is (C) genes involved in the cell cycle following a mutation become oncogenes. Oncogenes are genes that promote cell division in cancer cells. These genes arise from gain-of-function mutations that increase the activity of proto-oncogenes.
Detailed explanation-2: -Oncogenes in their proto-oncogene state drive the cell cycle forward, allowing cells to proceed from one cell cycle stage to the next. This highly regulated process becomes dysregulated due to activating genetic alterations that lead to cellular transformation.
Detailed explanation-3: -Oncogenes may cause normal cells to become cancer cells and grow in the body. Mutations that lead to the conversion of proto-oncogenes to oncogenes usually occur during a person’s lifetime and are not inherited from a parent.
Detailed explanation-4: -Introduction to Proto-oncogenes Mutations in proto-oncogenes are typically dominant in nature, and the mutated version of a proto-oncogene is called an oncogene. Often, proto-oncogenes encode proteins that function to stimulate cell division, inhibit cell differentiation, and halt cell death.