The kinases that drive the cell cycle are actually present at a constant concentration in a growing cell, but much of the time they are inactive. To be active, kinases must be attached to a

CELL DIVISION AND CANCEROUS CELLS

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A	centromere
B	centrosome
C	chromosome
D	cyclin

Explanation:

Detailed explanation-1: -Cyclin-dependent kinases In order to drive the cell cycle forward, a cyclin must activate or inactivate many target proteins inside of the cell. Cyclins drive the events of the cell cycle by partnering with a family of enzymes called the cyclin-dependent kinases (Cdks).

Detailed explanation-2: -Cell division in mammalian cells is driven by protein kinases that regulate progression through the various phases of the cell cycle. Cyclin-dependent kinases (Cdks) regulate cell cycle commitment, DNA synthesis and the onset of mitosis.

Detailed explanation-3: -Summary. Cyclin-dependent kinases (CDKs) are protein kinases characterized by needing a separate subunit-a cyclin-that provides domains essential for enzymatic activity. CDKs play important roles in the control of cell division and modulate transcription in response to several extra-and intracellular cues.

Detailed explanation-4: -The cell cycle is regulated by many cyclins and cyclin-dependent kinases (CDKs) that are a group of serine/threonine kinases. They form complexes with cyclins to stabilize, activate, and phosphorylate CDKs in the specific phases [6, 7].

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