AP BIOLOGY

Detailed explanation-1: -Metaphase leads to anaphase, during which each chromosome’s sister chromatids separate and move to opposite poles of the cell. Enzymatic breakdown of cohesin-which linked the sister chromatids together during prophase-causes this separation to occur.

Detailed explanation-2: -Anaphase is the fourth phase of mitosis, the process that separates the duplicated genetic material carried in the nucleus of a parent cell into two identical daughter cells.

Detailed explanation-3: -Anaphase: During anaphase, the centromere splits, allowing the sister chromatids to separate. The kinetochore spindle fibers shorten, allowing for 46 of the newly-freed chromatids to be dragged to one end of the cell and the remaining 46 chromatids to be dragged to the opposite end of the cell.

Detailed explanation-4: -Finally, in telomere regions, widely separated chromatids remain invisibly linked, presumably by catenation, with final separation during anaphase B. During this stage increased separation of poles and/or chromatin compaction appear to be the driving force(s).

Detailed explanation-5: -In anaphase, the sister chromatids separate from each other and are pulled towards opposite ends of the cell. The protein “glue” that holds the sister chromatids together is broken down, allowing them to separate. Each is now its own chromosome. The chromosomes of each pair are pulled towards opposite ends of the cell.