AP BIOLOGY

CELL DIVISION

CELL DIVISION AND CANCEROUS CELLS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which combination below is most likely to lead to the death of a potentially cancerous cell if there is a mutation in the cell’s proto-oncogene?
A
functioning telomerase gene, non-functioning stability gene, functioning tumor suppressor gene
B
non-functioning telomerase gene, non-functioning stability gene, non-functioning tumor suppressor gene
C
functioning telomerase gene, non-functioning stability gene, non-functioning tumor suppressor gene
D
functioning telomerase gene, functioning stability gene, functioning tumor suppressor gene
Explanation: 

Detailed explanation-1: -A mutation in a single allele of a tumor-suppressor gene is sufficient for a cell to become cancerous.

Detailed explanation-2: -Leading risk factors for preventable cancers are smoking, getting too much ultraviolet (UV) radiation from the sun or tanning beds, being overweight or having obesity, and drinking too much alcohol.

Detailed explanation-3: -The most commonly mutated gene in people with cancer is p53 or TP53. More than 50% of cancers involve a missing or damaged p53 gene. Most p53 gene mutations are acquired. Germline p53 mutations are rare, but patients who carry them are at a higher risk of developing many different types of cancer.

Detailed explanation-4: -Cancer is caused by changes to DNA. Most cancer-causing DNA changes occur in sections of DNA called genes. These changes are also called genetic changes. A DNA change can cause genes involved in normal cell growth to become oncogenes.

There is 1 question to complete.