CELL DIVISION
CELL DIVISION AND CANCEROUS CELLS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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proto-oncogenes & tumor suppressor genes
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DNA repair system
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apoptosis
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mutations
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Detailed explanation-1: -p53 controls G1 and G2 checkpoints activating or inhibiting genes involved in cell cycle, apoptosis and DNA repair. p53 is a nuclear DNA-binding phosphoprotein that exists normally as a tetramer able to bind specific DNA sequences.
Detailed explanation-2: -Apoptosis is the process of programmed cell death. It is used during early development to eliminate unwanted cells; for example, those between the fingers of a developing hand. In adults, apoptosis is used to rid the body of cells that have been damaged beyond repair.
Detailed explanation-3: -During apoptosis, cellular agents chop up the DNA and fragment the organelles and other cytoplasmic components of a cell.
Detailed explanation-4: -If damaged DNA is detected, p53 halts the cell cycle and recruits enzymes to repair the DNA. If the DNA cannot be repaired, p53 can trigger apoptosis, or cell suicide, to prevent the duplication of damaged chromosomes.