AP BIOLOGY

Detailed explanation-1: -Necroptosis, pyroptosis, ferroptosis, and NETosis are forms of programmed necrosis, wherein lytic cell death is mediated by an activatable genetic program.

Detailed explanation-2: -Programmed necrosis is defined as a genetically controlled cell death with morphological features such as cellular swelling (oncosis), membrane rupture, and release of cellular contents, in contrast to the organized packaging that occurs during apoptosis.

Detailed explanation-3: -Biological mechanisms In the strictest sense, programmed cell death may be applied to other forms of cell death that require gene expression without fulfilling some, or all, of the morphological criteria of apoptosis. Whatever the definition, studies clearly show that apoptosis is genetically regulated.

Detailed explanation-4: -There are three major types of morphologically distinct cell death: apoptosis (type I cell death), autophagic cell death (type II), and necrosis (type III). All three can be executed through distinct, and sometimes overlapping, signaling pathways that are engaged in response to specific stimuli.