CELL DIVISION
CELL DIVISION AND CANCEROUS CELLS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Ensure that all chromosomes have lined up in the center of the cell before cell division
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Ensure that spindle fibers have attached to all centromeres before cell division
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Ensure that DNA has been replicated before cell division
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All of these
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Detailed explanation-1: -The cell cycle is regulated by many cyclins and cyclin-dependent kinases (CDKs) that are a group of serine/threonine kinases. They form complexes with cyclins to stabilize, activate, and phosphorylate CDKs in the specific phases [6, 7].
Detailed explanation-2: -The four major mechanisms of CDK regulation are cyclin binding, CAK phosphorylation, regulatory inhibitory phosphorylation, and binding of CDK inhibitory subunits (CKIs).
Detailed explanation-3: -Cyclins drive the events of the cell cycle by partnering with a family of enzymes called the cyclin-dependent kinases (Cdks). A lone Cdk is inactive, but the binding of a cyclin activates it, making it a functional enzyme and allowing it to modify target proteins.
Detailed explanation-4: -Cyclin is a family of proteins that controls the progression of a cell through the cell cycle by activating cyclin-dependent kinase (CDK) enzymes or group of enzymes required for synthesis of cell cycle.
Detailed explanation-5: -When cyclins are synthesized, they act as an activating protein and bind to Cdks forming a cyclin-Cdk complex. This complex then acts as a signal to the cell to pass to the next cell cycle phase. Eventually, the cyclin degrades, deactivating the Cdk, thus signaling exit from a particular phase.