AP BIOLOGY

Detailed explanation-1: -Chromosome Movement in Mitosis Requires Microtubule Anchorage at Spindle Poles.

Detailed explanation-2: -Spindle fibres constitute mitotic and meiotic spindle during cell division. They are formed by microtubules and play an important role during nuclear division. They are responsible for the segregation of sister chromatids and movement of chromosomes during mitotic and meiotic division.

Detailed explanation-3: -The segregation of the replicated chromosomes is brought about by a complex cytoskeletal machine with many moving parts-the mitotic spindle. It is constructed from microtubules and their associated proteins, which both pull the daughter chromosomes toward the poles of the spindle and move the poles apart.

Detailed explanation-4: -The centromere is the part of a chromosome that links sister chromatids. During mitosis, spindle fibers attach to the centromere via the kinetochore.

Detailed explanation-5: -The movement of chromosomes is facilitated by a structure called the mitotic spindle, which consists of microtubules and associated proteins. Spindles extend from centrioles on each of the two sides (or poles) of the cell, attach to the chromosomes and align them, and pull the sister chromatids apart.