AP BIOLOGY

CELL DIVISION

CELL DIVISION AND CANCEROUS CELLS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which two two factors can inhibit (prevent/slow down) the progression of a cell through the cell cycle?
A
cell crowding and a decrease in surface area to volume ratio
B
cell crowding and decrease in growth hormone
Explanation: 

Detailed explanation-1: -Cell cycle checkpoints are critical to prevent the cell from progressing to the next phase of the cell cycle before the prior phase has been completed. Premature entry into the next phase of the cell cycle can result in catastrophic consequences for the cell and cell death.

Detailed explanation-2: -Two classes of genes, oncogenes and tumor suppressor genes, link cell cycle control to tumor formation and development. Oncogenes in their proto-oncogene state drive the cell cycle forward, allowing cells to proceed from one cell cycle stage to the next.

Detailed explanation-3: -In response to DNA damage, normal p53 binds DNA and promotes transcription of target genes. First, p53 triggers production of Cdk inhibitor proteins, pausing the cell cycle in G1 to allow time for repairs.

There is 1 question to complete.