AP BIOLOGY

CELL DIVISION

MEIOSIS AND GENETIC VARIATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Hemophilia is a recessive x-linked disorder. Which genotype represents a female who is a carrier for hemophilia?
A
XHXh
B
XhXh
C
XHXH
D
XhY
Explanation: 

Detailed explanation-1: -A female with a hemophilia allele on one X chromosome usually has a normal allele on her other X chromosome that can produce normal clotting factor, so she has some protection against having hemophilia. A female with one hemophilia allele and one normal allele is called heterozygous or a carrier.

Detailed explanation-2: -Hemophilia is an X-linked recessive hereditary disorder that classically affects males due to the presence of only one X chromosome in males. Females are usually carriers due to the presence of counterpart X chromosome, but many times manifestations of hemophilia are seen in heterozygous carrier females.

Detailed explanation-3: -Answer and Explanation: The genotype for a woman with hemophilia will be: XhXh. Where ‘Xh’ means gene carrying the mutation for hemophilia present in the X chromosome.

Detailed explanation-4: -Hemophilia is a sex-linked recessive disorder. The abnormal gene responsible for hemophilia is carried on the X chromosome.

There is 1 question to complete.