CELL DIVISION
MEIOSIS AND GENETIC VARIATION
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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XHXh
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XhXh
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XHXH
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XhY
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Detailed explanation-1: -A female with a hemophilia allele on one X chromosome usually has a normal allele on her other X chromosome that can produce normal clotting factor, so she has some protection against having hemophilia. A female with one hemophilia allele and one normal allele is called heterozygous or a carrier.
Detailed explanation-2: -Hemophilia is an X-linked recessive hereditary disorder that classically affects males due to the presence of only one X chromosome in males. Females are usually carriers due to the presence of counterpart X chromosome, but many times manifestations of hemophilia are seen in heterozygous carrier females.
Detailed explanation-3: -Answer and Explanation: The genotype for a woman with hemophilia will be: XhXh. Where ‘Xh’ means gene carrying the mutation for hemophilia present in the X chromosome.
Detailed explanation-4: -Hemophilia is a sex-linked recessive disorder. The abnormal gene responsible for hemophilia is carried on the X chromosome.