CELL DIVISION
MEIOSIS AND GENETIC VARIATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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growth factor and mitotic factor
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ATP synthase and a protease
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cyclin and tubulin
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cyclin and cyclin-dependent kinase
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cyclin-dependent kinase and PDGF
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Detailed explanation-1: -This suggested the key role of this molecule in the induction of the M-phase of cell cycle in all eukaryotic cells. After numerous efforts, MPF was identified as a complex of Cyclin-Dependent Kinase 1 (CDK1) and its regulatory subunit cyclin B [6–9].
Detailed explanation-2: -Two components of maturation-promoting factor or MPF are the cyclin-dependent kinase 1 (CDK1) subunit and the regulatory subunit cyclin.
Detailed explanation-3: -Cyclin is a component of maturation-promoting factor from Xenopus. Cell. 1990 Feb 9; 60(3):487-94. doi: 10.1016/0092-8674(90)90599-a.
Detailed explanation-4: -MPF is made up of two proteins, a protein kinase (cdc2 in yeast) whose levels are constant throughout the cell cycle and a cyclin (cdc 13 in yeast) whose levels fluctuate during the cell cycle.
Detailed explanation-5: -Maturation-promoting factor (MPF) MPF provides a good example of how cyclins and Cdks can work together to drive a cell cycle transition. Like a typical cyclin, M cyclin stays at low levels for much of the cell cycle, but builds up as the cell approaches the G 2start subscript, 2, end subscript/M transition.