AP BIOLOGY

Detailed explanation-1: -Metaphase leads to anaphase, during which each chromosome’s sister chromatids separate and move to opposite poles of the cell. Enzymatic breakdown of cohesin-which linked the sister chromatids together during prophase-causes this separation to occur.

Detailed explanation-2: -In anaphase, the sister chromatids separate from each other and are pulled towards opposite ends of the cell. The protein “glue” that holds the sister chromatids together is broken down, allowing them to separate. Each is now its own chromosome. The chromosomes of each pair are pulled towards opposite ends of the cell.

Detailed explanation-3: -During anaphase, the sister chromatids are separated simultaneously at their centromeres. The separated chromosomes are then pulled by the spindle to opposite poles of the cell. Anaphase ensures that each daughter cell receives an identical set of chromosomes.

Detailed explanation-4: -Chromosomes move poleward in anaphase along stationary microtubules that coordinately disassemble from their kinetochore ends. J Cell Biol (1987) 104 (1): 9–18. During the movement of chromosomes in anaphase, microtubules that extend between the kinetochores and the poles shorten.

Detailed explanation-5: -The chromosomes align at the center of the cell, and spindle fibers connect to the centromere of each chromosome and extend to centrioles at the 2 poles of the mitotic figure. Inanaphase the chromosomes divide along their longitudinal axes to form 2 daughter chromatids, which then migrate to opposite poles of the cell.