AP BIOLOGY

Detailed explanation-1: -In general, the nucleolus is visible only in interphase cells. Concomitant with the condensation of chromosomes as the cell approaches mitosis, the nucleolus is observed to decrease in size, then disappears as RNA synthesis stops.

Detailed explanation-2: -Late G2 phase. The cell has two centrosomes, each with two centrioles, and the DNA has been copied. At this stage, the DNA is surrounded by an intact nuclear membrane, and the nucleolus is present in the nucleus.

Detailed explanation-3: -The most obvious difference between interphase and mitosis involves the appearance of a cell’s chromosomes. During interphase, individual chromosomes are not visible, and the chromatin appears diffuse and unorganized.

Detailed explanation-4: -During interphase, the nucleolus becomes disrupted. Researchers think this nucleolar disruption results as a response to stress on the cell, due to the suppression of rRNA transcription via DNA damage, hypoxia or lack of nutrients.