AP BIOLOGY

Detailed explanation-1: -In nondisjunction, the separation fails to occur causing both sister chromatids or homologous chromosomes to be pulled to one pole of the cell. Mitotic nondisjunction can occur due to the inactivation of either topoisomerase II, condensin, or separase.

Detailed explanation-2: -Nondisjunction is the failure of homologous chromosomes (chromatids) to separate properly during meiotic cell division.

Detailed explanation-3: -Sometimes either homologous chromosomes or sister chromatids fail to separate properly during meiosis. This is called nondisjunction, and it produces gametes with an abnormal number of chromosomes.

Detailed explanation-4: -The difference between non-disjunction in meiosis I and meiosis II is that during meiosis I when genetic material is divided, non-disjunction results in abnormal homologous chromosomes. In meiosis II non-disjunction results in abnormal sister chromatids.