CELL DIVISION
THE CELL CYCLE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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G1
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G2
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M phase
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All of these are correct.
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Detailed explanation-1: -Each step of the cell cycle is monitored by internal controls called checkpoints. There are three major checkpoints in the cell cycle: one near the end of G1, a second at the G2/M transition, and the third during metaphase.
Detailed explanation-2: -The G2 checkpoint is used to prevent the cell from entering mitosis if there were errors in the replication of DNA during the S phase. Failure to pass the G2 checkpoint can result in apoptosis.
Detailed explanation-3: -The main cell cycle checkpoints are the G1/S checkpoint, the intra-S checkpoint, and the G2/M checkpoint [60]. The transition through stages of the cell cycle is regulated by the action of cyclin-dependent kinases, which are key targets for modulations induced by different cellular stimuli, including DNA damage.
Detailed explanation-4: -A checkpoint is one of several points in the eukaryotic cell cycle at which the progression of a cell to the next stage in the cycle can be halted until conditions are favorable. These checkpoints occur near the end of G1, at the G2/M transition, and during metaphase (Figure 1).
Detailed explanation-5: -There are many checkpoints in the cell cycle, but the three major ones are: the G1 checkpoint, also known as the Start or restriction checkpoint or Major Checkpoint; the G2/M checkpoint; and the metaphase-to-anaphase transition, also known as the spindle checkpoint.