AP BIOLOGY

Detailed explanation-1: -During anaphase, the sister chromatids are separated simultaneously at their centromeres. The separated chromosomes are then pulled by the spindle to opposite poles of the cell. Anaphase ensures that each daughter cell receives an identical set of chromosomes.

Detailed explanation-2: -A central feature of mitosis is segregation of sister chromatids to opposite poles during anaphase.

Detailed explanation-3: -The sister chromatids are pairs of identical copies of DNA joined at a point called the centromere. During anaphase, each pair of chromosomes is separated into two identical, independent chromosomes.

Detailed explanation-4: -Anaphase: During anaphase, the centromere splits, allowing the sister chromatids to separate. The kinetochore spindle fibers shorten, allowing for 46 of the newly-freed chromatids to be dragged to one end of the cell and the remaining 46 chromatids to be dragged to the opposite end of the cell.

Detailed explanation-5: -The spindle fibers contract during anaphase, separating the sister chromatids and pulling them to opposite poles of the cell.