AP BIOLOGY

Detailed explanation-1: -Metaphase leads to anaphase, during which each chromosome’s sister chromatids separate and move to opposite poles of the cell.

Detailed explanation-2: -Anaphase: During anaphase, the centromere splits, allowing the sister chromatids to separate. The kinetochore spindle fibers shorten, allowing for 46 of the newly-freed chromatids to be dragged to one end of the cell and the remaining 46 chromatids to be dragged to the opposite end of the cell.

Detailed explanation-3: -In anaphase II, the sister chromatids separate and are pulled towards opposite poles of the cell. In telophase II, nuclear membranes form around each set of chromosomes, and the chromosomes decondense.

Detailed explanation-4: -Sister chromatids separate during anaphase in a three-stage program as directed by interaxis bridges.

Detailed explanation-5: -During anaphase II, microtubules from each spindle attach to each sister chromatid at the kinetochore. The sister chromatids then separate, and the microtubules pull them to opposite poles of the cell.