CELL DIVISION
THE CELL CYCLE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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If the DNA in a cell is damaged, what will happen when it undergoes mitosis?
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The damage is repaired before it divides.
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That cell will never divide.
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Each new cell that is produced will have the damage.
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One of the new cells will have the damage, but the other one will not.
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Explanation:
Detailed explanation-1: -By inducing chromosome segregation defects, mitotic DNA damage can lead to telomere fusions and structural aberrations leading to chromosome translocations.
Detailed explanation-2: -DNA damage can affect normal cell replicative function and impact rates of apoptosis (programmed cell death, often referred to as ‘cellular senescence’). Alternatively, damage to genetic material can result in impaired cellular function, cell loss, or the transformation of healthy cells to cancers.
Detailed explanation-3: -Mitosis Inhibits DNA Double-Strand Break Repair to Guard Against Telomere Fusions. Science, 2014; DOI: 10.1126/science.
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