CELL DIVISION
THE CELL CYCLE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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G1 checkpoint
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G2 checkpoint
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M checkpoint
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G0 checkpoint
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Detailed explanation-1: -The G2/M checkpoint is controlled by Cdc2/cyclinB, and their negative regulators including p21Cip1 and p27 [9]. Weakened G2/M checkpoint under therapeutic setting may trigger cell death via mitotic catastrophe for cells with unrepairable DNA lesions and mitosis machinery.
Detailed explanation-2: -The cell will only pass the checkpoint if it is an appropriate size and has adequate energy reserves. At this point, the cell also checks for DNA damage. A cell that does not meet all the requirements will not progress to the S phase.
Detailed explanation-3: -At the G2 checkpoint, the cell checks for: DNA damage. DNA replication completeness.
Detailed explanation-4: -Gap 2 Phase This last stage is all about prepping the cell for mitosis or meiosis. During G2, the cell has to grow some more and produce any molecules it still needs to divide. This includes assembly of the microtubules, which will make up an important structure called the spindle during mitosis.