AP BIOLOGY

CELL DIVISION

THE CELL CYCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The normal function of a tumor suppressor gene is
A
to produce growth signals
B
to code for proteins that inhibit, or slow, cell division
C
to cause the cell to move faster through the cell cycle
D
to attack cancer cells in the body
Explanation: 

Detailed explanation-1: -Tumor suppressor genes represent the opposite side of cell growth control, normally acting to inhibit cell proliferation and tumor development. In many tumors, these genes are lost or inactivated, thereby removing negative regulators of cell proliferation and contributing to the abnormal proliferation of tumor cells.

Detailed explanation-2: -Tumor suppressor genes are normal genes that slow down cell division or tell cells to die at the right time (a process known as apoptosis or programmed cell death). When tumor suppressor genes don’t work properly, cells can grow out of control, which can lead to cancer.

Detailed explanation-3: -Tumor Suppressor Proteins Control Cell Growth Tumor suppressor proteins regulate orderly cell growth and differentiation by sensing the surrounding environment, transmitting signals to the nucleus, and directly affecting transcription, translation, survival, or cell division.

Detailed explanation-4: -Types of Tumor Suppressor Genes Telling cells to slow down and stop dividing. Repairing damage to cellular DNA that results from dividing and could lead to cancer.

Detailed explanation-5: -Answer and Explanation: Tumor-suppressor genes, in normal cells, encode proteins that inhibit cell division. The best known of these genes is TP53, so-called because its encoded protein, p53, has a molecular weight of 53 000 daltons.

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