AP BIOLOGY

CELL DIVISION

THE CELL CYCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The stage of mitosis in which chromatids are replicated, spindle fibers begin to form, and the nuclear membrane disintegrates
A
metaphase
B
prophase
C
telophase
D
anaphase
Explanation: 

Detailed explanation-1: -During prophase, the nucleus disappears, spindle fibers form, and DNA condenses into chromosomes (sister chromatids).

Detailed explanation-2: -Spindle. The spindle starts to form during prophase of mitosis. Kinetochores on the spindle attach to the centromeres of sister chromatids.

Detailed explanation-3: -Prophase is the first phase of mitosis, the process that separates the duplicated genetic material carried in the nucleus of a parent cell into two identical daughter cells. During prophase, the complex of DNA and proteins contained in the nucleus, known as chromatin, condenses.

Detailed explanation-4: -Today, mitosis is understood to involve five phases, based on the physical state of the chromosomes and spindle. These phases are prophase, prometaphase, metaphase, anaphase, and telophase.

Detailed explanation-5: -During prophase, the chromosomes condense and centrosomes move to opposite sides of the nucleus, initiating formation of the mitotic spindle.

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