CELL DIVISION
THE CELL CYCLE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Checkpoints repeat
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Checkpoints don’t function properly
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Mitosis is repeated
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Cells shrink
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Detailed explanation-1: -If cells don’t pass the G1 checkpoint, they may “loop out” of the cell cycle and into a resting state called G0, from which they may subsequently re-enter G1 under the appropriate conditions. At the G1 checkpoint, cells decide whether or not to proceed with division based on factors such as: Cell size. Nutrients.
Detailed explanation-2: -If the cell cycle checkpoints fail, cells that are not replicating correctly will be allowed to continue to grow and multiply. This is dangerous because the cell cycle mutations that are causing the failure can be passed on through the cell lineage.
Detailed explanation-3: -Genetic analysis of human cancers has revealed that proteins involved in the G1/S checkpoint are inactivated in the majority of cases, and that alterations of the DNA damage checkpoint are likely to be responsible for resistance of tumour cells to chemotherapic agents or irradiation.