AP BIOLOGY

CELL DIVISION

THE CELL CYCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What would be the result of a mutation that allows a cell to move past checkpoint G2 even though DNA replication has not been completed?
A
The daughter cell would be small and possibly not able to store enough nutrients within the cell to survive. It can also cause cancer.
B
The DNA in the daughter cells would not be able to complete and the cells would not survive.
C
The chromosomes might end up in the wrong daughter cell. For example, one cell might get both copies of chromosomes while the other gets none.
Explanation: 

Detailed explanation-1: -Predict the result of a mutation that allows a cell to move past checkpoint G2 even though the DNA replication has not been completed. the DNA in the daughter cells would not be complete and the cells would not survive.

Detailed explanation-2: -The next checkpoint is the G2 checkpoint, where the cell checks and makes sure the DNA replicated correctly before beginning mitosis. If the cell does not pass this checkpoint, it commences apoptosis and dies.

Detailed explanation-3: -Answer and Explanation: If the cell cycle checkpoints fail, cells that are not replicating correctly will be allowed to continue to grow and multiply. This is dangerous because the cell cycle mutations that are causing the failure can be passed on through the cell lineage.

Detailed explanation-4: -Which mutation would allow the cell to pass the G1 checkpoint when it should not? A mutation in Rb, preventing it from associating with E2F.

Detailed explanation-5: -If errors or damage are detected, the cell will pause at the G 2start subscript, 2, end subscript checkpoint to allow for repairs. If the checkpoint mechanisms detect problems with the DNA, the cell cycle is halted, and the cell attempts to either complete DNA replication or repair the damaged DNA.

There is 1 question to complete.