CELL DIVISION
THE CELL CYCLE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Because DNA polymerase works in only one direction
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Because the bases are positively and negatively charged
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It increases efficiency
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It prevents mutations
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Detailed explanation-1: -Answer and Explanation: DNA polymerase moves in opposite directions because it is only able to attach to a free 3’ end. DNA polymerase is a three dimensional enzyme and can only attach to a specific configuration of substrate, which is the free 3’ OH group on a nucleotide.
Detailed explanation-2: -DNA Polymerase Only Moves in One Direction As previously mentioned, DNA polymerase can only add to the 3’ end, so the 5’ end of the primer remains unaltered. Consequently, synthesis proceeds immediately only along the so-called leading strand.
Detailed explanation-3: -Since DNA polymerase requires a free 3’ OH group for initiation of synthesis, it can synthesize in only one direction by extending the 3’ end of the preexisting nucleotide chain. Hence, DNA polymerase moves along the template strand in a 3’–5’ direction, and the daughter strand is formed in a 5’–3’ direction.
Detailed explanation-4: -The Leading and Lagging Strands DNA polymerase can only synthesize new strands in the 5′ to 3′ direction. Therefore, the two newly-synthesized strands grow in opposite directions because the template strands at each replication fork are antiparallel.