AP BIOLOGY

Detailed explanation-1: -The link reaction takes place in the mitochondrial matrix. The link reaction takes place in the mitochondrial matrix and converts pyruvate into a molecule called acetyl coenzyme A (acetyl CoA). This stage does not produce any energy in the form of ATP but does produce reduced NAD and acetyl CoA.

Detailed explanation-2: -Aerobic respiration commences with the oxidation of pyruvic acid. This is called link reaction or gateway step as it links glycolysis in cytoplasm and Krebs cycle in mitochondrial matrix. Here pyruvate is oxidised to acetyl CoA which enters the Krebs cycle for further oxidation.

Detailed explanation-3: -The inner and outer membranes of mitochondria define three compartments within the organelle, each with its distinct role and corresponding protein components. The innermost compartment, surrounded by the inner membrane, is the mitochondrial matrix.

Detailed explanation-4: -The mitochondrial matrix contains a large variety of enzymes, including those that convert pyruvate and fatty acids to acetyl CoA and those that oxidize this acetyl CoA to CO2through the citric acid cycle. Large amounts of NADH (and FADH2) are produced by these oxidation reactions.