CELL RESPIRATION
GLYCOLYSIS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Kinase
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Phosphorylase
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Dehydrogenase
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Isomerase
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Detailed explanation-1: -Glyceraldehyde-3-phosphate dehydrogenase (GAPDH, EC:1.2. 1.12) is an important enzyme in the glycolysis process. In the presence of inorganic phosphate (Pi), GAPDH catalyzes the conversion of D-glyceraldehyde-3-phosphate (G3P) to 1, 3-diphosphoglycerate (BPG), accompanying the reduction of NAD+ to NADH.
Detailed explanation-2: -Phosphoglycerate kinase (PGK1) (EC 2.7.2.3) is ubiquitously expressed and catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1, 3-diphosphoglycerate to 3-phosphoglycerate.
Detailed explanation-3: -So the correct option is ‘Dephosphorylation. ‘
Detailed explanation-4: -Glyceraldehyde-3-phosphate or 3-phosphoglyceraldehyde (PGAL) is converted into 1, 3-bisphosphoglyceric acid or 1, 3-bisphosphoglycerate (BPGA). During this conversion NAD+ is converted to NADH + H+. i.e. two redox equivalents are removed (in the form of two hydrogen atoms) from PGAL and transferred to a molecule of NAD+.