AP BIOLOGY

CELL RESPIRATION

GLYCOLYSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
How does glycolysis lead to ATP synthesis?
A
Glucose provides the phosphate for ADP to synthesize ATP
B
Glycolysis splits the glucose molecule to create G3P
C
High energy electrons are stored in NADH for the ETC
D
Acetyl CoA is synthesized for the Krebs cycle
Explanation: 

Detailed explanation-1: -NADH and FADH2 molecules formed during Glycolysis and Krebs Cycle carry their electrons to the electron transport chain. The electron transport chain creates a proton gradient that ultimately leads to the production of a large amount of ATP.

Detailed explanation-2: -This is because glycolysis happens in the cytosol, and NADH can’t cross the inner mitochondrial membrane to deliver its electrons to complex I. Instead, it must hand its electrons off to a molecular “shuttle system” that delivers them, through a series of steps, to the electron transport chain.

Detailed explanation-3: -During glycolysis, glucose ultimately breaks down into pyruvate and energy; a total of 2 ATP is derived in the process (Glucose + 2 NAD+ + 2 ADP + 2 Pi–> 2 Pyruvate + 2 NADH + 2 H+ + 2 ATP + 2 H2O). The hydroxyl groups allow for phosphorylation. The specific form of glucose used in glycolysis is glucose 6-phosphate.

Detailed explanation-4: -Electron transport is the final stage of aerobic respiration. In this stage, energy from NADH and FADH2 is transferred to ATP. During electron transport, energy is used to pump hydrogen ions across the mitochondrial inner membrane, from the matrix into the intermembrane space.

Detailed explanation-5: -During oxidative phosphorylation, electrons derived from NADH and FADH2 combine with O2, and the energy released from these oxidation/ reduction reactions is used to drive the synthesis of ATP from ADP.

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