AP BIOLOGY

CELL RESPIRATION

GLYCOLYSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The first enzymes that convert glucose into glucose-6-P are
A
Hexokinase
B
PFK1
C
Phosphofructokinase
D
Aldolase
Explanation: 

Detailed explanation-1: -Hexokinase converts glucose to glucose 6-phosphate, trapping the glucose molecule inside the cell, thus starting off the process of glycolysis.

Detailed explanation-2: -Glucose is first phosphorylated to glucose 6-phosphate by an enzyme called ‘Hexokinase’ in the presence of Mg2+. So, the answer is ‘Hexokinase’.

Detailed explanation-3: -Glucose-6-phosphate (G6P) is changed into fructose-6-phosphate (F6P) by phosphoglucoisomerase (phosphoglucose isomerase) in the second step.

Detailed explanation-4: -Hexokinase is the initial enzyme of glycolysis, catalyzing the phosphorylation of glucose by ATP to glucose-6-P. It is one of the rate-limiting enzymes of glycolysis. Its activity declines rapidly as normal red cells age.

Detailed explanation-5: -Glucose-6-phosphatase (G6Pase), an enzyme found mainly in the liver and the kidneys, plays the important role of providing glucose during starvation. Unlike most phosphatases acting on water-soluble compounds, it is a membrane-bound enzyme, being associated with the endoplasmic reticulum. In 1975, W.

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