AP BIOLOGY

Detailed explanation-1: -Glyceraldehyde 3-phosphate dehydrogenase (abbreviated GAPDH) (EC 1.2. 1.12) is an enzyme of about 37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules.

Detailed explanation-2: -During glycolysis, the major energy generating step involves: pyruvate kinase phosphoglycerate kinase Phosphofructokinase glyceraldehyde-3-dehydrogenase.

Detailed explanation-3: -Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a highly conserved enzyme within the glycolytic pathway. GAPDH catalyzes the transformation of glyceraldehyde 3-phosphate to glycerate-1, 3-biphosphate, a process accompanied by the production of NADH.

Detailed explanation-4: -Glyceraldehyde 3-phosphate or G3P is the product of the Calvin cycle. It is a 3-carbon sugar that is the starting point for the synthesis of other carbohydrates. Some of this G3P is used to regenerate the RuBP to continue the cycle, but some is available for molecular synthesis and is used to make fructose diphosphate.

Detailed explanation-5: -In a reversible reaction, glyceraldehyde 3-phosphate is converted by glyceraldehyde phosphate dehydrogenase to an energy-rich intermediate, 1, 3-bisglycerophosphate (or 3-phosphoglyceroy 1-phosphate).