AP BIOLOGY

CELL RESPIRATION

GLYCOLYSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the major energy generating step in glycolysis?
A
Phosphofructokinase
B
Hexokinase
C
Phosphoglycerate kinase
D
Glyceraldehyde-3-P dehydrogenase
Explanation: 

Detailed explanation-1: -Glyceraldehyde 3-phosphate dehydrogenase (abbreviated GAPDH) (EC 1.2. 1.12) is an enzyme of about 37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules.

Detailed explanation-2: -During glycolysis, the major energy generating step involves: pyruvate kinase phosphoglycerate kinase Phosphofructokinase glyceraldehyde-3-dehydrogenase.

Detailed explanation-3: -Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a highly conserved enzyme within the glycolytic pathway. GAPDH catalyzes the transformation of glyceraldehyde 3-phosphate to glycerate-1, 3-biphosphate, a process accompanied by the production of NADH.

Detailed explanation-4: -Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is one such enzyme. It catalyzes the conversion of glyceraldehyde 3-phosphate to glycerate-1, 3-biphosphate, and results in production of NADH.

Detailed explanation-5: -In a reversible reaction, glyceraldehyde 3-phosphate is converted by glyceraldehyde phosphate dehydrogenase to an energy-rich intermediate, 1, 3-bisglycerophosphate (or 3-phosphoglyceroy 1-phosphate).

There is 1 question to complete.