AP BIOLOGY

CELL RESPIRATION

GLYCOLYSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Where is ATP synthase located in the mitochondrion?
A
cytosol
B
electron transport chain
C
outer mitochondria membrane
D
inner mitochondria membrane
Explanation: 

Detailed explanation-1: -Human mitochondrial (mt) ATP synthase, or complex V consists of two functional domains: F1, situated in the mitochondrial matrix, and Fo, located in the inner mitochondrial membrane. Complex V uses the energy created by the proton electrochemical gradient to phosphorylate ADP to ATP.

Detailed explanation-2: -The inner mitochondrial membrane contains many copies of a protein called the F0F1ATPase. This is also called ATP synthase. It consists of two parts: the F0 component spans the membrane and provides a channel for protons to move into the matrix from the intermembrane space.

Detailed explanation-3: -In eukaryotes, the ATP synthase complex is located in the inner membrane of mitochondria, with ATP synthesis reaction occurring on the membrane side toward matrix compartment. In plants, the enzyme is in addition localized in the thylakoid membrane of chloroplasts, with the ATP-forming-moiety facing the stroma.

Detailed explanation-4: -At the inner mitochondrial membrane, a high energy electron is passed along an electron transport chain. The energy released pumps hydrogen out of the matrix space. The gradient created by this drives hydrogen back through the membrane, through ATP synthase.

Detailed explanation-5: -Mitochondria are surrounded by a double-membrane system, consisting of inner and outer mitochondrial membranes separated by an intermembrane space (Figure 10.1). The inner membrane forms numerous folds (cristae), which extend into the interior (or matrix) of the organelle.

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