CELL RESPIRATION
GLYCOLYSIS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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3-phosphoglycerate to 2-phosphoglycerate
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fructose-6-phosphate to fructose 1, 6 bisphosphate
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glyceraldehyde-3-phosphate to 1, 3-bisphosphoglycerate
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glucose-6-phosphate to fructose-6-phosphate
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Detailed explanation-1: -Phosphofructokinase 1 (PFK1) catalyzes the irreversible conversion of fructose-6-phosphate (F6P) and ATP into fructose-1, 6-bisphosphate (F1, 6BP) and ADP.
Detailed explanation-2: -Reactions a, c and d are irreversible in glycolysis. The reaction ‘d’ catalysed by Phosphofructokinase is the rate limiting reaction of glycolysis.
Detailed explanation-3: -The reactions of glycolysis convert glucose 6-phosphate to pyruvate. The entire process is cytosolic. Glucose 6-phosphate is reversibly isomerized to form fructose 6-phosphate.
Detailed explanation-4: -Fructose-1, 6-bisphosphate (F-1, 6-BP) is an important intermediate in glucose metabolism, particularly in cancer. Gluconeogenesis and glycolysis require fructose-1, 6-bisphosphonates 1 (FBP1) and fructose-bisphosphate aldolase A (ALDOA), which participate in F-1, 6-BP conversion.