AP BIOLOGY

CELL RESPIRATION

OXIDATIVE PHOSPHORYLATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What would occur if all available hydrogen ions were used by ATP synthase?
A
It would increase the ph of the mitochondrial intermembrane space
B
ATP synthase activity decreases the levels of inorganic phosphate in the mitochondrial matrix
Explanation: 

Detailed explanation-1: -Hydrogen ions in the matrix space can only pass through the inner mitochondrial membrane through a membrane protein called ATP synthase. As protons move through ATP synthase, ADP is turned into ATP. The production of ATP using the process of chemiosmosis in mitochondria is called oxidative phosphorylation.

Detailed explanation-2: -Eventually these hydrogen atoms flow down their concentration gradient through a protein called ATP synthase. ATP synthase uses the energy stored in the gradient to make ATP. If the membrane was permeable to hydrogen ions at other points no gradient could be established and thus no ATP would be made.

Detailed explanation-3: -When hydrogen ions are pumped from the mitochondrial matrix across the inner membrane and into the intermembrane space, the result is the creation of proton-motive force (d is correct). The proton-motive force describes the force created by the tendency of hydrogen ions to move down their concentration gradient.

Detailed explanation-4: -The upper part of the ATP synthase complex rotates when a new hydrogen ion enters. Once three protons have entered the matrix space, there is enough energy in the ATP synthase complex to synthesize one ATP. In this way, the energy in the hydrogen ion gradient is used to make ATP.

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