AP BIOLOGY

CELL RESPIRATION

THE KREBS CYCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
T/F-The Krebs cycle is a cyclic process because the product of step 8, is the reactant in step 1
A
True
B
False
Explanation: 

Detailed explanation-1: -Step 8 of the Krebs cycle: Malate-Dehydrogenase This final reaction closes the krebs cycle. here, L-malate is transformed into oxal acetate. The hydroxy group of L-malate (in yellow) is oxidized to an -keto group and the released protons are picked up by NAD+, which then is reduced to NADH + H+.

Detailed explanation-2: -It is an eight-step process. Krebs cycle or TCA cycle takes place in the matrix of mitochondria under aerobic condition. Step 1: The first step is the condensation of acetyl CoA with 4-carbon compound oxaloacetate to form 6C citrate, coenzyme A is released.

Detailed explanation-3: -During the first step of Krebs cycle, oxalo acetic acid reacts with acetyl CoA to form citric acid. As Krebs cycle is a cyclic pathway, the initial reactant oxalo acetic acid also acts as final product of the cycle.

Detailed explanation-4: -The eight steps of the citric acid cycle is a loop because the compounds used at the beginning are regenerated in the last stage to be used again.

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