CELL RESPIRATION
THE KREBS CYCLE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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oxaloacetate + acetyl-CoA + ADP + Pi + 3NAD1 + FAD
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oxaloacetate + acetyl-CoA + ADP + Pi + 3NAD+ + 6FAD
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oxaloacetate + acetyl-CoA + ADP + Pi + 6NAD1 + FAD
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Detailed explanation-1: -The overall reaction for the citric acid cycle is:2acetylgroups+6NAD++2FAD+2ADP+2Piyields4CO2+6NADH+6H++2FADH2+2ATP.
Detailed explanation-2: -This cycle involves a series of reactions involving a (1) a substrate, Oxaloacetate, that is modified in every reaction, (2) Acetyl–CoA, from which energy is extracted, (3) energy transport reactants, which collect the extracted energy, and (4) the controlling enzymes, which regulate the steps of the cycle.
Detailed explanation-3: -Because citrate synthase is inhibited by the final product of the citric acid cycle as ATP, ADP (adenosine diphosphate) works as an allosteric activator of the enzyme as ATP is formed from ADP. Therefore, the rate of the cycle is reduced when the cell has a high level of ATP.
Detailed explanation-4: -Thus, one acetyl CoA forms one ATP molecule. Hence, the two will form 2 ATP molecules in one cycle of the Krebs cycle.