AP BIOLOGY

Detailed explanation-1: -Ketoglutarate dehydrogenase is an essential enzyme that converts ketoglutaric acid to succinyl CoA in Krebs’ cycle. Such a conversion oxidises the ketoglutaric acid of hydrogen and also removes one CO2. Hence it is a oxidation and decarboxylation reaction. So the answer is ‘Oxidation and decarboxylation’.

Detailed explanation-2: -Alpha-ketoglutarate dehydrogenase (-KGDH) is a highly regulated enzyme, which could determine the metabolic flux through the Krebs cycle. It catalyses the conversion of -ketoglutarate to succinyl-CoA and produces NADH directly providing electrons for the respiratory chain.

Detailed explanation-3: -Step in the TCA cycle related to the oxidative decarboxylation step: The process that leads to succinyl CoA production by-ketoglutarate is connected to oxidative decarboxylation. The enzyme-ketoglutarate dehydrogenase catalyzes this process.

Detailed explanation-4: -Oxidative decarboxylation is a process in which carbon dioxide is produced through the removal of a carbon group as a result of oxidation reactions. There are vital in many biological processes such as the citric acid cycle.