AP BIOLOGY

Detailed explanation-1: -Experimentation by Francesco Redi in the 17th century presented the first significant evidence refuting spontaneous generation by showing that flies must have access to meat for maggots to develop on the meat.

Detailed explanation-2: -He did note that maggots were found on the exterior surface of the cloth that covered the jar. Redi successfully demonstrated that the maggots came from fly eggs and thereby helped to disprove spontaneous generation.

Detailed explanation-3: -John Needham. Louis Pasteur. Francesco Redi. Spallanzani and Pasteur both disproved spontaneous generation in their experiments.