AP BIOLOGY

HEREDITY

LINKED GENES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A man with Huntington’s disease has several children with a normal woman. What percent of their children will get Huntington’s disease?
A
0
B
25
C
50
D
75
E
100
Explanation: 

Detailed explanation-1: -If a parent has the Huntington’s disease gene, there’s a: 1 in 2 (50%) chance of each of their children developing the condition – affected children are also able to pass the gene to any children they have.

Detailed explanation-2: -With dominant diseases like Huntington’s Disease (HD), it is usually pretty easy to figure out risks. Generally if one parent has it then each child has a 50% chance of having it too. And if neither parent has the disease, then odds are that none of the kids will either. Huntington’s is a dominant genetic disease.

Detailed explanation-3: -HD is inherited as an autosomal dominant disorder, meaning that each child of an affected parent has a 50:50 chance of inheriting the genetic mutation that causes HD, and men and women are equally likely to inherit the mutation.

Detailed explanation-4: -Every child conceived naturally to a parent who carries the Huntington’s gene has a 50% chance of inheriting it. Living with the knowledge that you are at risk can be very worrying. You may feel that you would prefer to know for certain whether or not you have the faulty copy of the gene.

Detailed explanation-5: -The genetic risk to children A person with a Huntington’s disease affected parent has a 50% risk of having inherited the Huntington’s disease gene. Each child of that person has a 25% chance of inheriting the condition. But this ‘25%’ only applies while the person is untested.

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