AP BIOLOGY

HEREDITY

MUTATIONS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A frameshift mutation ____ (select all that apply)
A
Changes the reading frame for all codons that follow
B
is the insertion/deletion of a nucleotide in the DNA sequence
C
is when one nucleotide is substituted for another
D
Shifts the entire sequence by one or more nucleotides
E
moves a segment of one chromosome to a nonhomologous chromosome.
Explanation: 

Detailed explanation-1: -Frameshift mutations arise when the normal sequence of codons is disrupted by the insertion or deletion of one or more nucleotides, provided that the number of nucleotides added or removed is not a multiple of three.

Detailed explanation-2: -Listen to pronunciation. (FRAYM-shift myoo-TAY-shun) An insertion or deletion involving a number of base pairs that is not a multiple of three, which consequently disrupts the triplet reading frame of a DNA sequence.

Detailed explanation-3: -Frameshift mutations are deletions or additions of 1, 2, or 4 nucleotides that change the ribosome reading frame and cause premature termination of translation at a new nonsense or chain termination codon (TAA, TAG, and TGA).

Detailed explanation-4: -Insertions, deletions, and duplications can all be frameshift variants. Some regions of DNA contain short sequences of nucleotides that are repeated a number of times in a row.

There is 1 question to complete.